This Week in Nature

In Nature this week, a duo from Pennsylvania State University presents new data describing the genomic organization of human transcript initiation complexes. Noting that only a small part of the human genome is coding despite pervasive transcription, the researchers asked whether non-coding transcription arises at promoters, and investigated the interaction of the initiation factors TATA box binding protein, transcription factor IIB, and RNA polymerase II.

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