This Week in Nature

In this week's Nature, a Max Planck Institute for Biology of Ageing-led team reports on the discovery that mutations in maternally transmitted mitochondrial DNA, or mtDNA, may aggravate aspects of normal human aging. The investigators created a series of mouse mutants to investigate the impact of inherited mtDNA mutations on aging, and they found that maternally transmitted mtDNA mutations can induce mild aging phenotypes in some wild-type mice.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.