In this week’s Nature, researchers from the University of Massachusetts Medical School reported on the silencing of a third copy of chromosome 21 that causes Down’s syndrome in a cell culture model of the disorder, marking a step forward towards “chromosome therapy.” The scientists used zinc finger nucleases to insert an inducible transgene version of a gene called XIST into cultured stem cells from Down’s syndrome patients.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in Science

Ancient Wheat

Funds Needed

This Week in PNAS

In Cell this week: dynamics of protein profusion and localization, melanoma classification schemes, and more.

A company says it can generate likenesses of people based on their genetic profiles.

IBM's Watson is learning how to treat leukemia as a fellow at the MD Anderson Cancer Center, according to the Washington Post.

In PNAS this week: ancestry and admixture in Brazilians, characterization of novel double-stranded RNA mycovirus, and more.