In this week’s Nature, researchers from the University of Massachusetts Medical School reported on the silencing of a third copy of chromosome 21 that causes Down’s syndrome in a cell culture model of the disorder, marking a step forward towards “chromosome therapy.” The scientists used zinc finger nucleases to insert an inducible transgene version of a gene called XIST into cultured stem cells from Down’s syndrome patients.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in Science

Ancient Wheat

This Week in PNAS

This Week in Nature

In Science this week: self-assembly of DNA components in solution, and more.

Genetics and Molecular Research retracts two gastric cancer papers for being "substantially equal" to other papers, according to Retraction Watch.

A new analysis indicates that the Ebola virus behind the current West African outbreak is mutating at about the same rate as other Ebola viruses.

With the launch of Scott Kelly into space today, the study of him and his earthbound brother to disentangle the effects of life in space from the effects of genetics kicks off.