In this week’s Nature, researchers from the University of Massachusetts Medical School reported on the silencing of a third copy of chromosome 21 that causes Down’s syndrome in a cell culture model of the disorder, marking a step forward towards “chromosome therapy.” The scientists used zinc finger nucleases to insert an inducible transgene version of a gene called XIST into cultured stem cells from Down’s syndrome patients.

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

A team of researchers in Portugal has examined the genomic basis for racing pigeons' athleticism and navigational skills, finding it's likely polygenic.

Wired reports that diagnostic firms continue to seek, post-Theranos, the ability to diagnose diseases from small amounts of blood.

In Science this week: analysis of DNA from ancient North Africans, and more.