This Week in Nature

In Nature this week, researchers from Baylor College of Medicine report on the discovery of potential targets for the neurodegenerative disease spinocerebellar ataxia type 1, or SCA1, through the use of a novel strategy of genetic network screening. Noting that the severity of SCA1 is associated with the accumulation of mutant ataxin 1 protein, the team used cross-species genetic screening to identify druggable targets that modulate levels of this protein.

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