This Week in Nature

Based on genomic, transcriptomic, and proteomic analyses of nearly 400 tumors, the Cancer Genome Atlas Research Network team uncovered four subtypes of endometrial cancer, as it reports in Nature this week. These four categories subdivide the tumors based on their mutation frequency: POLE ultramutated, microsatellite instability hypermutated, copy-number low, and copy-number high tumors.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.