This Week in Nature

In this week's Nature, a team of researchers from the Institute for Research in Biomedicine in Spain report on the role of the RNA-binding protein CPEB1, which controls mRNA translation, in regulating alternative 3'-UTR processing. They found that CPEB1 shuttles to the nucleus, where it co-localizes with splicing factors and mediates shortening of hundreds of mRNA 3' UTRs, modulating their translation efficiency in the cytoplasm.

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