This Week in Nature

In Nature this week, scientists from the University of Minnesota report on the identification of a likely source of genetic mutations required for cancer development. The team specifically found that the DNA cytosine deaminase APOBEC3B is upregulated in most primary breast tumors and breast cancer cell lines. "Tumors that express high levels of APOBEC3B have twice as many mutations as those that express low levels and are more likely to have mutations in TP53," they write.

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