This Week in Nature

The University of Texas MD Anderson Cancer Center's Ronald DePinho and his colleagues report in Nature this week that homozygous deletions in redundant essential housekeeping genes could create possible targets for cancer therapeutics. The researchers write that ENO1 is a redundant housekeeping gene that is deleted in glioblastoma; ENO1 encodes part of endolase, which is a necessary part of glycolysis. ENO2, which is only expressed in neural tissues, also encode endolase.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.