This Week in Nature

A team led by investigators at the University of Rochester in New York this week show that "nuclear-retained transcripts containing expanded CUG-CUGexp — repeats are unusually sensitive to antisense silencing," and that, in a transgenic mouse model of myotonic dystrophy type 1, the systematic administration of antisense oligonucleotides causes "a rapid knockdown of CUGexpRNA in skeletal muscle, correcting the physiological, histopathologic and transcriptomic features of the disease." Overall, as the Rochester-led team reports in Nature, "these results provide

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.