This Week in Nature

A team led by investigators at the University of Rochester in New York this week show that "nuclear-retained transcripts containing expanded CUG-CUGexp — repeats are unusually sensitive to antisense silencing," and that, in a transgenic mouse model of myotonic dystrophy type 1, the systematic administration of antisense oligonucleotides causes "a rapid knockdown of CUGexpRNA in skeletal muscle, correcting the physiological, histopathologic and transcriptomic features of the disease." Overall, as the Rochester-led team reports in Nature, "these results provide

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

The World Health Organization has announced the members of its gene-editing committee, according to NPR.

DARPA is working on developing algorithms that gauge the credibility of research findings, Wired reports.

The American Society of Breast Surgeons recommends all women diagnosed with breast cancer be offered genetic testing, the Washington Post says.

In Science this week: comparison of modern, historical rabbit exomes uncovers parallel evolution after myxoma virus exposure; and more.