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In a paper published online in advance in Nature this week, a team led by investigators at the Massachusetts Institute of Technology shows that "cognitive capacities in the neurodegenerating brain are constrained by an epigenetic blockade of gene transcription that is potentially reversible." The MIT-led team says that histone deacetylase 2 mediates this blockade, adding that it "associates with and reduces the histone acetylation of genes important for learning and memory, which

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The World Bank is seeking approval for a $12 billion plan to provide low-income nations with funds to procure SARS-CoV-2 vaccines, according to Reuters.

The Washington Post reports that Herbert Tabor, who worked at the US National Institutes of Health for 77 years, has died at 101.

Science writes that public health officials and others are debating whether cycle threshold values should be included on SARS-CoV-2 results.

In Nucleic Acids Research this week: online database of SARS-CoV-2 protein structures, atlas of the human brain, and more.