This Week in Nature

In a Nature paper published online in advance this week, investigators at the Whitehead Institute in Cambridge, Mass., and elsewhere show that the histone demethylase lysine-specific demethylase 1, or LSD1 "is essential in decommissioning enhancers during the differentiation of mouse embryonic stem cells." The Whitehead-led team says LSD1 "occupies enhancers of active genes that are critical for control of the state of ESCs," but is not essential for embryonic stem cell identity

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.