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In a Nature paper published online in advance this week, investigators at the Whitehead Institute in Cambridge, Mass., and elsewhere show that the histone demethylase lysine-specific demethylase 1, or LSD1 "is essential in decommissioning enhancers during the differentiation of mouse embryonic stem cells." The Whitehead-led team says LSD1 "occupies enhancers of active genes that are critical for control of the state of ESCs," but is not essential for embryonic stem cell identity

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23andMe has launched a new tool that estimates someone's risk of developing severe COVID-19 if infected, Bloomberg reports.

The Guardian reports that Pasteur Institute researchers are halting their development of a SARS-CoV-2 vaccine following disappointing initial results.

The Wall Street Journal reports that an increased number of younger patients have been hospitalized as the new SARS-CoV-2 strain spread across the UK.

In Cell this week: proteomic patterns among COVID-19 affected tissue samples, transcriptome atlas of developing intestines, and more.