This Week in Nature

In a Nature paper published online in advance this week, investigators at the Whitehead Institute in Cambridge, Mass., and elsewhere show that the histone demethylase lysine-specific demethylase 1, or LSD1 "is essential in decommissioning enhancers during the differentiation of mouse embryonic stem cells." The Whitehead-led team says LSD1 "occupies enhancers of active genes that are critical for control of the state of ESCs," but is not essential for embryonic stem cell identity

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.