This Week in Nature | GenomeWeb

This Week in Nature

In a Nature paper published online in advance this week, investigators at the Whitehead Institute in Cambridge, Mass., and elsewhere show that the histone demethylase lysine-specific demethylase 1, or LSD1 "is essential in decommissioning enhancers during the differentiation of mouse embryonic stem cells." The Whitehead-led team says LSD1 "occupies enhancers of active genes that are critical for control of the state of ESCs," but is not essential for embryonic stem cell identity

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