In Nature this week, researchers at Rockefeller University report on a "microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells." More specifically, the team shows that miR-126 "non-cell-autonomously regulates endothelial cell recruitment to metastatic breast cancer cells in vitro and in vivo" and that it "suppresses metastatic endothelial recruitment, metastatic angiogenesis, and metastatic colonization through coordinate targeting