Researchers in France this week identify a germline missense substitution in MITF, Mi-E318K, that "occurred at a significantly higher frequency" in patients affected with melanoma, renal cell carcinoma, or both, compared with controls. "Overall, Mi-E318K carriers had a higher than fivefold increased risk of developing melanoma, RCC or both cancers," the authors write in a paper published online in advance in Nature.

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The apple has traveled westward and eastward along the Silk Road, according to a new genetic analysis.

In Nature this week: GWAS data used to reposition drugs for psychiatric use, and more.

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