This Week in Nature

The Broad Institute's David Sabatini and colleagues report in Nature on their development and use of a method to uncover novel cancer targets. Their method uses a negative-selection RNAi screen that they then applied to find metabolic genes that are necessary for tumorigenesis in breast cancer.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.