This Week in Nature

In Nature this week, researchers at Rockefeller University in New York say intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway. The researchers generated humanized DC-SIGN mice to demonstrate that the anti-inflammatory activity of immunoglobulin can be recreated by the transfer of bone-marrow-derived sFc-treated hDC-SIGN+ macrophages or dendritic cells into naive recipients.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.