This Week in Nature

In a paper published online in advance in Nature this week, an international team led by investigators at Imperial College London shows that the homing endonuclease gene I-Sce1 "can substantially increase its transmission to the progeny in transgenic mosquitoes of the human malaria vector Anopheles gambiae." More specifically, I-Sce1 quickly invades mosquito populations such that it validates mathematical models of homing endonuclease gene transmission dynamics.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.