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In a paper published online in advance in Nature this week, a team led by investigators at the University of Copenhagen presents evidence to suggest TET1 has a role in transcriptional repression, such that it "binds a significant proportion of Polycomb group target genes" and also "associates and co-localizes with the SIN3A co-repressor complex." As a result of its investigation, the team suggests that TET1 "contributes to the regulation of DNA methylation fidelity" by opposing ab

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