This Week in Nature

In a paper published online in advance in Nature this week, a team led by investigators at the University of Copenhagen presents evidence to suggest TET1 has a role in transcriptional repression, such that it "binds a significant proportion of Polycomb group target genes" and also "associates and co-localizes with the SIN3A co-repressor complex." As a result of its investigation, the team suggests that TET1 "contributes to the regulation of DNA methylation fidelity" by opposing ab

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.