This Week in Nature

In a paper published online in advance in Nature this week, MIT's Tyler Jacks and his colleagues describe the "suppression of lung adenocarcinoma progression by Nkx2-1," the NK2-related homeobox transcription factor. In a KrasLSL-G12D/+;p53flox/flox mouse model, the team found that "Nkx2-1 negativity is pathognomonic of high-grade poorly differentiated tumors." In their subsequent gain- and loss-of-function manipulations, the researchers found that the transcription factor controls tumor differentiation but also limits its metastatic potential.

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In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.