This Week in Nature

In a paper published online in advance in Nature this week, researchers at the M.D. Anderson Cancer Center and their international colleagues report that the chromatin regulator tripartite motif-containing 24 "functions in humans as a reader of dual histone marks by means of tandem plant homeodomain and bromodomain regions." Aberrant TRIM24 expression, the team shows, correlates negatively with survival in breast cancer patients.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.