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In a paper published online in advance in Nature this week, researchers at the Children's Hospital of Philadelphia, along with their international colleagues, show that "common polymorphisms at the LMO1 locus are strongly associated with susceptibility to developing neuroblastoma." In a genome-wide association study of 2,251 patients and 6,097 controls, the CHOP-led team found an enriched signal at LMO1 in individuals who had the most aggressive neuroblastomas.

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Moderna reports its vaccine is effective against new SARS-CoV-2 strains, though it is also developing a booster, according to the New York Times.

A new analysis suggests the B.1.1.7 strain of SARS-CoV-2 could be deadlier than previous ones, according to the Guardian.

NPR reports Merck is halting the development of its two candidate SARS-CoV-2 vaccines following disappointing Phase 1 results.

In PLOS this week: gene mutation linked to inherited venous thrombosis, lncRNA patterns in the Asian tiger mosquito, and more.