This Week in Nature

In a paper published online in advance in Nature this week, a team led by researchers at Oregon Health and Science University describes "ploidy conveyor" as a source of genetic variation in hepatocytes. It shows that in mouse polyploidy hepatocytes, multipolar mitotic spindles frequently form — which "can result in one-step ploidy reversal to generate offspring with halved chromosome content," the team writes.

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Researchers are refining a tool to predict a woman's risk of developing breast cancer, according to the Guardian.

According to Stat News, the partial government shutdown in the US could soon affect the ability of the Food and Drug Administration to review new drugs.

In PNAS this week: gypsy moth genome sequenced, phylogenomic analysis of Polyneopterans, and more.

CNN reports that people's genes tend to have a greater influence on their risk of developing disease than their environment, but it varies by phenotype.