This Week in Nature

In an advance, online publication of Nature this week, investigators at Yale University School of Medicine and their international colleagues report their use of whole-exome sequencing to identify "recessive WDR62 mutations in severe brain malformations," including microcephaly, pachygyria with cortical thickening, and hypoplasia of the corpus callosum.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.