This Week in Nature

In Nature this week, investigators in Tokyo and Toronto report that "OTUB1, a deubiquitinating enzyme, is an inhibitor of DSB-induced chromatin ubiquitination." The authors write that they were surprised to find that OTUB1 binds and inhibits UBC13, consequently suppressing RNF168-dependent poly-ubiquitination "independently of its catalytic activity." The team suggests that "pharmacological targeting of the OTUB1–UBC13 interaction might enhance the DNA damage response."

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American scientists find themselves once again warning the Trump administration not to dismiss science, the New Yorker report.

A new study suggests CRISPR could be used to save coral reefs from dying off, Forbes reports.

Researchers have found that the i-motif shape of DNA previously observed in the lab also exists in human cells, and that it may serve a purpose.

In PNAS this week: a genomic, transcriptomic, and metabolomic analysis of the tea plant, Arabidopsis thaliana's adaptations to specific local environments, and more.