This Week in Nature

In Nature this week, an international research team reports their examination of the alterations in chromatin structure that coincide with pluripotency and genome activation. Using a zebrafish model, the team mapped the location of the repressive H3K27me3 and the activating H3k4me3 histone molecules. While neither were detected before the maternal-zygotic transition, more than 80 percent of the genes were marked by H3K4me3 after genome activation.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more