This Week in Nature

In this week’s issue of Nature, an international research team describes how structural signatures can be used to distinguish between the effects of mutation and selection in cancer genomes. Graham Bignell of the Wellcome Trust Sanger Institute and his colleagues identified 2,428 somatic homozygous deletions in 746 cancer cell lines.

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In a survey, about half of Canadian government scientists say they still feel as though they cannot speak freely, ScienceInsider reports.

Clinicians in China are moving ahead with a number of CRISPR trials, NPR reports, as the US embarks on its first.

The Atlantic reports that biohacker Josiah Zayner regrets injecting himself with the CRISPR gene-editing tool on stage.

In Nature this week: genomic approaches applied to study Neolithic and Bronze Age Europeans, and more.