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In this week's issue of Nature, a UK research team reports that they have identified large, rare chromosomal copy number changes linked to early obesity. In a group of 300 Caucasian individuals with early onset obesity, including 143 with developmental delays, the researchers found recurrent, rare deletions of various sizes affecting a chromosome 16 region called 16p11.2 — previously tied to conditions such as autism and mental retardation.

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