This Week in Nature

A news feature in Nature looks at the work of the "genome finishers," particularly Deanna Church, who spend their days sorting out problems found in the human reference genome. Some critics say Church and her colleagues in the Genome Reference Consortium shouldn't bother — Lincoln Stein says it is "more of an abstract exercise than one that's going to have a practical impact" — but Church says the little things count, particularly as genomics moves into the clinic.

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