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In this week's issue of Nature, which celebrates the magazine's 140th birthday, scientists from Singapore and the Netherlands use a new technique to study how genome-wide chromatin interactions affect estrogen receptor-alpha-regulated gene expression.

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.