This Week in Nature

In the current issue of Nature, scientists led by the University of Pennsylvania's Shelley Berger used chIP to study how Sir2 in yeast, which is known to deacetylate histone H4 lysine 16 and play a role in aging, affects cellular longevity. She found that in old yeast cells, a decrease in Sir2 was met by an increase in H4 lysine 16 acetylation and loss of histones at specific subtelomeric regions, resulting in "compromised transcriptional silencing at these loci."

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.