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Published in Nature's early online edition, researchers at Children's Hospital Boston have used stem cells to study why cancer appears less in people with Down syndrome. Following up on previous studies, they found that one gene on chromosome 21, DSCR1, is increased in expression in Down's syndrome tissues and in a mouse model of Down's syndrome. DSCR1, Down's syndrome candidate region-1, encodes a protein that suppresses angiogenesis by the calcineurin pathway.

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The Lancet has made changes to its peer-review process in response to its recent retraction of a COVID-19-related paper, Science reports.

The New York Times reports that a series of emails show how Department of Health and Human Services officials sought to silence the Centers for Disease Control and Prevention.

A new initiative aims to move Australia's genome sequencing labs onto one system, the Sydney Morning Herald reports.

In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.