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In the early online edition of Genome Research this week, the University of Manchester's Andrew Sharrocks is lead author on a paper that used ChIP-chip to find all the target genes of the ETS-domain transcription factor ELK1. His team found that there are two modes by which ELK1 targets genes, and that one of the most "prominent groups of genes forming the ELK1 target network" are those that are part of the basal transcriptional machinery, the spliceosome, and the ribosome.

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