The University of Montreal's Philip Awadalla, with Canadian and American collaborators, describes ties between rare alleles in the meiotic recombination-related gene PRDM9 and childhood leukemia in an early, online Genome Research study. The team picked up rare, maternally inherited PRDM9 variants when they tested two French Canadian siblings with B-cell precursor acute lymphoblastic leukemia and their unaffected parents.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.