Researchers at the Yale School of Medicine and at the University of Pennsylvania report an RNA-seq-based circadian transcriptome of Drosophila melanogaster brain from wild-type and period-null clock-defective animals in a paper published online in advance in Genome Research this week. "We identify several hundred transcripts whose abundance oscillates with 24-hour periods in either constant darkness or 12 hour light/dark diurnal cycles, including a number of non-coding RNAs that were not identified in previous microarray studies," the authors write.