In a paper published online in advance in Genome Research this week, researchers describe their high-throughput method for interrogating transcription factor binding specificity, based on systematic evolution of ligands — or SELEX — by exponential enrichment and massively parallel sequencing of proteins expressed in mammalian cells.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.