In an early online article, scientists led by CSHL's Rob Martienssen have resequenced the fission yeast genome following mutagenesis to "readily identify a novel mutant involved in heterochromatic silencing." Candidate mutant genes were put back into a wild-type strain to reproduce the mutant phenotype, which allowed them to find an allele thatencodes an E2 ubiquitin ligase as being responsible for the swi*603 mutant phenotype.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.