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In an early online article, scientists led by CSHL's Rob Martienssen have resequenced the fission yeast genome following mutagenesis to "readily identify a novel mutant involved in heterochromatic silencing." Candidate mutant genes were put back into a wild-type strain to reproduce the mutant phenotype, which allowed them to find an allele thatencodes an E2 ubiquitin ligase as being responsible for the swi*603 mutant phenotype.

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.