In Genome Research this week, European researchers used bead arrays and bisulfite sequencing to find methylation changes linked to systemic lupus erythrematosus in pairs of identical twins who were discordant for the autoimmune disease — especially at genes involved in immune function. Their follow-up experiments suggest those with lupus tend to have lower levels of 5-methylcytosine, less methylation at certain genes, and higher expression of these genes.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.