Using a technique called TraDIS, for transposon directed insertion-site sequencing, scientists at the Wellcome Trust Sanger Institute led work that mapped 370,000 unique transposon insertion sites to the Salmonella enterica serovar Typhi chromosome. The density and resolution -- "an average of one every 13 base pairs," they say -- has allowed them to assay genome-wide for "essential genes" and create a list of candidates.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.