In the April issue of Genome Research, Harvard's Martha Bulyk and Josh LaBaer led research that scanned yeast transcription factors for their binding specificity across the genome. Building off ChIP-chip data, they created genome-wide binding profiles for 89 known and predicted yeast TFs over more than 2.3 million gapped and ungapped 8-bp sequences, finding 50 new or different DNA-binding site motifs.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.