In the March issue of Genome Research, work led by Evan Eichler describes the first systematic and genome-wide analysis of segmental duplications and CNVs in the modern domesticated dog, Canis familiaris. Using tiling arrays that covered all predicted segmental duplications, Eichler's team performed array CGH across 17 breeds and a gray wolf, identifying 3,583 CNVs. They found that these CNVs span 429 genes that are involved in many biological processes such as olfaction, immunity, and gene regulation.

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Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.

Feb
21
Sponsored by
L7 Informatics

This webinar will provide a first-hand look at how Gradalis, a clinical-stage immunotherapy developer, is using an information management solution from L7 to streamline its research, clinical, and manufacturing operations.

Feb
26
Sponsored by
Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the Firestone Institute for Respiratory Health at McMaster University developed a cellular and molecular phenotyping pipeline using archived samples of lung tissue derived from patients diagnosed with fibrotic interstitial lung disease.