In Genome Biology this week, research led by Katharine Webb at the Institute of Developmental Genetics in Neuherberg, Germany, showed that there are specific transcriptional networks that influence addiction. Using a model of a mutant zebrafish that doesn't respond to amphetamines, they combined microarray analysis with qPCR and in situ hybridization to identify and validate specific brain areas that responded to amphetamine in wild-type siblings.

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