A Washington University team used transcriptome sequence data to track down recurrent shifts in long intergenic non-coding RNA (lncRNA) profiles in lung cancer. Using existing RNA sequences produced using 567 lung adenocarcinoma or lung squamous cell carcinoma samples for The Cancer Genome Atlas and other projects, the researchers identified thousands of previously undescribed lncRNAs. These included 100 lncRNAs with expression patterns that differed in the lung cancers compared to matched normal controls.

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