A team from the University of Lausanne and the Swiss Institute of Bioinformatics present evidence of conserved microRNA editing sites in the genomes of mammals and other animals. By searching for examples of RNA and DNA mismatches in human, rhesus macaque, mouse, opossum, platypus, and chicken small RNA sequence datasets, the researchers determined that adenosine-to-inosine editing in miRNAs tends to occur at deeply conserved sites.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.