University of California, Los Angeles, cell and developmental biology researcher Matteo Pellegrini and colleagues used bisulfite sequencing to track cross-generation DNA methylation marks in two parental mouse strains and their hybrid offspring. Based on DNA methylation patterns in liver samples from eight of the parental or hybrid mice, the team determined that at least a subset of between-strain methylation differences in mice are heritable.

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

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In Science this week: analysis of DNA from ancient North Africans, and more.