The European Bioinformatics Institute's Tim Massingham and Nick Goldman present All Your Base, which they call "a fast and accurate probabilistic approach to base calling," in a paper published online in advance in Genome Biology this week. Massingham and Goldman say their approach "improves on the best existing base callers, especially when comparing the number of error-free reads." All Your Base is available online, here, they add.
In a another report published online in advance, Harvard University's Alexander Meissner and his colleagues report on the January Joint Keystone Symposium on Epigenomics and Chromatin Dynamics. The size of the meeting reflected "the excitement and many developments in this area," they write.