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This Week in Genome Biology: Feb 29, 2012

The European Bioinformatics Institute's Tim Massingham and Nick Goldman present All Your Base, which they call "a fast and accurate probabilistic approach to base calling," in a paper published online in advance in Genome Biology this week. Massingham and Goldman say their approach "improves on the best existing base callers, especially when comparing the number of error-free reads." All Your Base is available online, here, they add.

In a another report published online in advance, Harvard University's Alexander Meissner and his colleagues report on the January Joint Keystone Symposium on Epigenomics and Chromatin Dynamics. The size of the meeting reflected "the excitement and many developments in this area," they write.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.