In a paper published online in advance in Genome Biology, the University of Surrey's Tom Mendum and his colleagues present a representative Tn5 library for Neisseria meningitidis, which they used to investigate the metabolism of the human commensal and pathogen. The team created a genome-scale metabolic network, which it says "was able to distinguish essential and non-essential genes as predicted by the global mutagenesis." Overall, Mendum et al.

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