Published yesterday in Genome Biology, Chad Nusbaum at the Broad Institute is the lead author on a paper describing a novel method for closing non-structural gaps in the human genome. Even though the human genome is "finished," the most recent release contains 260 euchromatic gaps. In this work, they present an approach for closing these gaps using 454 sequencing, and as proof of principle, apply it to closing all three remaining non-structural gaps in chromosome 15.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Researchers test gene therapy targeting a different cancer protein in a new trial, the New York Times reports.

Pennsylvania State University researchers found that salivary microRNAs could predict which kids would have longer concussion symptoms, according to NPR.

The Associated Press reports Alex Azar, the new Department of Health and Human Services secretary nominee, made millions of dollars as a pharmaceutical executive.

In PNAS this week: immune profiling of breast cancer, transposable element patterns in rice, and more.