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Investigators at the Broad Institute led by Chad Nusbaum describe in an advance online publication of Genome Biology an automated, scalable approach to Solution Hybrid Selection capture, which they say "provides a dramatic increase in scale and throughput of sequence-ready libraries produced." Nusbaum et al. have also injected "a series of in-process quality control checkpoints" into their protocol, which they add, can be useful for the standard, manual method.

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