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In a method paper published online in Genome Biology this week, the University of Washington's Jay Shendure and his colleagues describe an approach for shotgun fragment library construction based on high-density in vitro transposition. When applied to the sequencing of a human genome, Shedure et al. say their method produced coverage biases "comparable with conventional protocols," though it is more efficient than other methods.

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23andMe has launched a new tool that estimates someone's risk of developing severe COVID-19 if infected, Bloomberg reports.

The Guardian reports that Pasteur Institute researchers are halting their development of a SARS-CoV-2 vaccine following disappointing initial results.

The Wall Street Journal reports that an increased number of younger patients have been hospitalized as the new SARS-CoV-2 strain spread across the UK.

In Cell this week: proteomic patterns among COVID-19 affected tissue samples, transcriptome atlas of developing intestines, and more.