In an article in last week's Genome Biology, scientists used sys bio tools to study how some highly disordered proteins avoid degradation in order to carry out their function. Combining sequencing, gene expression, and proteomic information, they were able to see that not only do disordered proteins have a greater proportion of predicted ubiquitination sites, but also their transcripts have higher proportions of predicted miRNA target sites and higher mRNA decay rates.

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