In Genome Biology this week, a team of researchers in Germany compared target genes of TFIIB and NC2 transcription factors in human B cells and analyzed the associated core promoter architectures. TFIIB occupancy is positively correlated with gene expression, the researchers write, and the majority of promoters are GC-rich and lack defined core promoter elements. They also found that NC2 binds to a highly related target gene set. "TFIIB and NC2 are global players that occupy active genes," the team writes.

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have an account?
Login Now.

Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.